SAGE Genie: A suite with panoramic view of gene expression
نویسندگان
چکیده
منابع مشابه
SAGE Genie: a suite with panoramic view of gene expression.
I f the achievement of complete sequencing of the one-dimensional genetic codes of the human genome can be compared with man landing on the moon, the interpretation of genomic instruction in a four-dimensional biological context, such as during development and diseases, will prove to be a much more challenging and daunting task than that of getting man back from the moon to the earth. One of th...
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To gain a molecular understanding of kidney functions, we established a high-resolution map of gene expression patterns in the human kidney. The glomerulus and seven different nephron segments were isolated by microdissection from fresh tissue specimens, and their transcriptome was characterized by using the serial analysis of gene expression (SAGE) method. More than 400,000 mRNA SAGE tags were...
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To identify molecular alterations involved in the initiation and progression of breast carcinomas, we analyzed the global gene expression profiles of normal mammary epithelial cells and in situ, invasive, and metastatic breast carcinomas using serial analysis of gene expression (SAGE). We identified sets of genes expressed only or most abundantly in a specific stage of breast tumorigenesis or i...
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Design of biometric algorithms and evaluation of performance goes hand in hand. It is important to constantly evaluate and analyze progress being at various levels of biometrics design. This evaluation can be of three types: at algorithm-level, at scenario-level, and at operational-level, roughly corresponding to the maturity of the biometric. Given the young nature of gait as a biometric sourc...
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A comparison study of short SAGE versus GeneChip and long SAGE was conducted to determine if data were interchangeable between the techniques. Although SAGE and Affymetrix chip expression levels showed a significant correlation using the set of genes for which there was reliable and unambiguous mapping from tag-to-gene identification, correlation coefficients were low (0.51 for the Spearman's c...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2002
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.192436299